I am installing a new top on my workbench and hope to have it finished today. I use 3/4 MDF for the top and intentionally built my workbench so I could change the top as needed. This way I can drill, saw or whatever without being concerned I am destroying a $300.00 plus workbench.
As far as clamps go I use the clamps made by Incra, Rockler and others by installing a series of 1/4-20 T-Nuts around 4 inches apart from end to end and side to side over 3/4 of the table top. Once the T-Nuts are installed I place a sheet of cheap plywood over them so they won't pop out then screw the top down into workbench frame. I have 4 of the clamps and they are screwed down using plastic knobs with 4 inch 1/4-20 hex head bolts. I use my B&D screwdriver to tighten and loosen the clamps. Works like a charm.
This the clamp style I am talking about:
When something is advertised as being foolproof there is always a better class of fool that comes along to prove them wrong.