How about a vacuum system.
There's plenty out there but heres a quickie:
https://www.usroutertools.com/storm-vac-system-for-cnc-routers-p/bbv-sa2-220.htm
& do your own plumbing.
Relatively thin Acrylic cuts better when vacuumed. Tape costs & just a hassle.
So having a combo of both clamps & vac (hybrid top(s) - 4D ) is best suited.
Spend the $$$, do it right & call it george.
There's plenty out there but heres a quickie:
https://www.usroutertools.com/storm-vac-system-for-cnc-routers-p/bbv-sa2-220.htm
& do your own plumbing.
Relatively thin Acrylic cuts better when vacuumed. Tape costs & just a hassle.
So having a combo of both clamps & vac (hybrid top(s) - 4D ) is best suited.
Spend the $$$, do it right & call it george.