It's not science, but I used the Bosch, which was an upgrade for me. Then, I switched to Festool, and my hands never felt better. Haven't tried gloves, but see no need to, either.
For flat surfaces, I use the
6" RO 150 FEQ Rotex. I only use the Rotex feature after a bad end grain glue up, really. The normal mode is all I need to flatten my cutting boards & serving pieces. The 6" pad is 20% larger than the 5", and that's a material difference in a volume business. It's a heavy beast ... which is why I also bought another.
For edges, corners, and quick jobs, I use the
ETS EC125/3 EQ 5" Random Orbit Sander. The weight is fantastic. I still get hand fatigue if I do a particularly long session of edge sanding, but it's not about the vibration. Again, this sander was a huge upgrade.
Pairing both sanders with a dust extractor has eliminated almost all of the dust in my shop from the finish sanding process.
So, yes, I've drunk the Kool Aid. I know Festool is not cheap, but my only regret is that I waited so long to buy them.