work clamping

If you are doing a production run of identical parts then reference ledges plus cams or wedges like Gaffboat shows above will probably be your best bet. You don't need t-track or threaded inserts or vacuum, but can simply screw down the ledges and cam or wedge backer block. If you have room on your bed for more than one unique part you can jig them all up, and use different coordinate systems with each to not even have to set your X/Y/Z origins between cut sessions or days.

You can make ledges that have a slightly sloped overhang to also hold down the parts while they are being cut.

4D

The Nebula bed area is 37" x 50", with 5" of Z travel although only roughly 3" is available above the MDF bed.

We also have a Nebula in our college furniture design shop. It sits next to our Meteor from the same company. The longer gantry has more flex when challenging the router/spindle with deep profile cuts in hardwoods. There is vibration that happens. More when the router is in the middle of the gantry, and when making cuts that move in the Y direction. Fine for most work, but I've pretty much stopped using it for such cuts that could be done on our Meteor instead.

4D