But how many times will pocket holes get that much pressure exerted on them when the whole project is put together? But never use pocket holes myself, closest I ever came to them was using dowels. Usually just use glue blocks.
When I was a kid I was taught:
Use screws when you expect to take something apart later.
Use nails when you do not expect to ever take something apart.
Use hide glue when you may have to take something apart later
Use regular glue for joints and such.
"It ain't what you're told, it's what you know." - Granny Weatherwax
Gather the villagers, pitchforks, torches; we march at dusk!
It's the first five days after the weekend that are the worst.